A Healthy Mouth for a Sound Heart Poor oral health and cardiovascular disease may be connected. According to several studies, patients with periodontal (gum) disease often show a higher risk for heart attack and stroke, though a direct cause-and-effect link between the factors has yet to be established. Periodontal disease, as well as deep tooth decay, can allow oral bacteria and the toxins they produce to enter the bloodstream. This can provoke a chronic inflammatory response and a buildup of plaque along the arterial walls, one theory goes, increasing the likelihood of heart attack or stroke. So, by brushing, flossing, and visiting the dentist regularly, you could actually prevent cardiovascular disease.