Male Infertility Comes with Age Men, like women, have reduced odds of successful fertilization at age 35, a recent French study has found, younger than is generally thought. And the likelihood of pregnancy drops drastically in men over 40. The study, conducted on 12,200 couples, showed that sperm from men older than 40 produced only a 10% pregnancy rate and a one-third higher prevalence of miscarriage. Though this evidence helps dispel the myth of the ever-virile man, in-vitro fertilization (IVF) provides a viable solution. Through IVF, laboratory technicians can select the most robust sperm and inject it directly into the egg, lowering the risk of miscarriage and the time it takes for a pregnancy to stick.